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Dosing, sampling and poisoning

Gelatin capsules

来源:本站 作者:玉研仪器 Time: 2016-12-01 Source: Site Author: Jade research instrument

Detailed introduction

Capsules for animal administration are very suitable for oral administration of capsules to rats and mice.

Capsule filling of the drug is performed first, and then the administration operation is performed on rats or mice.


Yuyan Instrument Co., Ltd. also provides domestic custom-made capsules: enteric-soluble and gastric-soluble mice and mice irrigation capsules, a total of four models, please contact us



In the case where various tested drugs require oral administration, capsules are more suitable and convenient than other methods:
Capsules can be used to easily administer powder or solid medicines, or in cases where a catheter cannot be used for administration;
Corresponding to some odorous or bitter medicine, it can be easily administered to reduce animal suffering;
The administration of individual preparations is quite convenient;
In order to exert the effect continuously for a long time, the capsule can assist in full absorption;
It is very suitable to use when capsules are needed in the experimental protocol.
Compared with the medicine mixed in the feed for feeding, the capsule method is more accurate and no residue;


There are many specifications and models to choose from, welcome to inquire.



Dosing Kits include capsules, funnel, stand, tamper, dosing device & instructional video


  • Ideal for materials that are insoluble, form poor suspensions, are affected by excipients or are odorous and distasteful, eg, sustained release beadlets, paint flakes, chromic oxide marker
  • For capsule size, species, weight, and lower GI drug delivery size see table below. Capsule holders available for dip coating in enteric solutions. Capsule sinkers available for testing in disintegration test apparatus.
  • Size 9 can be used for intra-colonic delivery via rectal insertion in rats> 200-250gm.
  • Save time and money by eliminating validation of suspension / solution homogeneity.
  • Eliminate excipients absorption affects.

Fill Materials:

Dry materials in any form
(powder, beadlets, crystals,
paint flakes), pastes, and
non-aqueous liquids.

Disintegration Time:

Within 10 minutes in stomach.

Dosing Time & Acceptance:
<1 min. (30-45 minutes for 60 rats).
> 98% successful dosing after minimal experience (3-4 placebo doses per rat).


on sizes 9el, 9 and 9h.

Animal Weight:

See below

Lower GI Drug Delivery:

See below

Parameter Size 9el Size 9 Size 9h Size M
Species & Weight Rats 200g + Rats 200g
(min 150g)
Guinea Pig 300g +
Hamsters & Rats 150g + Mice 25g +
Species & Weight Lower GI Delivery n / a Rat 200g +
Guinea Pig 300g +
Hamster
& Rat 150g +
Guinea Pig 300g +
Mice 30g +
Capsule Body Capacity 0.08 ml 0.025 ml 0.013ml 0.004 ml
Fill Weight (materials with density 1g / ml) 80 mg 25 mg 13mg 4 mg
External Diameter Maximum 2.71 mm 2.71 mm 2.71 mm 1.27 mm
Length When Locked Maximum 23.0 mm 8.4 mm 5.1mm 8.4 mm

Surface area locked capsule in sq mm for enteric coating.

Not Applicable 68mm 2 42 mm 2 31mm 2
Weight Empty (Cap & Body) Average 1 17 mg 10 mg 5mg ~ 2 mg
Colors Available Clear & Opaque Clear & Opaque Clear & Opaque White
For a specific net fill weight tare the weight of each capsule body individually and then fill or use a pre-weighed amount of powder for each capsule.

Tip: Order syringes for each technician to speed dosing.

Charger, dispenser set



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