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Pain and inflammation research

Hot plate instrument

来源:本站 作者:玉研仪器 Time: 2016-09-21 Source: Site Author: Jade research instrument

Detailed introduction

Hot Plate Analgesia T est Meter Mice and Rats) 测试大鼠和小鼠的疼痛反应时间,进行快速精确地筛选麻醉型镇痛药物 ,更多详情敬请来电咨询) Hot Plate Analgesia Tact Meter Mice and Rats ( Tests the pain response time of rats and mice, and performs rapid and accurate screening of narcotic analgesics . For more details, please see Please inquire)


Model: 39 type (hot plate instrument), PE34 (hot and cold plate instrument)

 

The hot plate pain tester tests the pain response time of rats and mice to quickly and accurately screen narcotic analgesics. For example, for a group of rats, before taking the drug, measure the average time of licking the paw of the group of rats on the hot plate. This time corresponds to the response time of the rat to thermal stimulation. After taking an analgesic or anesthetic drug, Measure the average time that the rats in this group licked their paws on the hot plate. This time corresponds to the response time of the rats to the thermal stimulus after taking the drug. The comparison of the two time values is used to evaluate the analgesic or anesthetic drugs on the rats. effect.

 

Hot Plate Analgesia test is used for latency testing in rats and mice. The animals are placed on a black anodized, aluminum plate (11 ”X 10.5” X ¾ ”, 275mm X 263mm X 15mm) which is heated uniformly.

 

特点: Main Features of Hot Plate Pain Tester :  

 

可测量大鼠和小鼠 温度步进量0.1摄氏度 Ø Can measure the temperature step of rat and mouse 0.1 degree Celsius

控制保持精度+/- 0.1摄氏度 Ø Control maintain accuracy +/- 0.1 degrees Celsius

温度范围从0到75℃ Ø Temperature range from 0 to 75 ° C

时间精度为0.01秒 Ø Time accuracy is 0.01 seconds

标准计算机打印口,输出 RS-232输出 ØStandard computer print port, output RS-232 output

 

Dimensions:

Electronics-18 "X 18"

120 / 240V  

CE

Part #

Description

39

Hot Plate Analgesia Meter mice rats

39RE

Hot Plate Analgesia Meter Rat Enclosure (Square)

39ME

Hot Plate Analgesia Meter Mouse Enclosure (Round)

Series 8

Software





Related Literature:

Substitution of a mutant α2a-adrenergic receptor via “hit and run” gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing…

PP Lakhlani, LB MacMillan, TZ Guo…-Proceedings of the…, 1997-National Acad Sciences

… B6,129 male mice, ≈3 months old, were placed on an enclosed hot-plate (IITC Inc.); the
temperature of the plate was ramped at 6 ° C / min from 43 ° C to 52 ° C. When a mouse licked a hind
paw, the mouse was removed from the hot plate and the temperature recorded…

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Hot plate versus tail flick: evaluation of acute tolerance to continuous morphine infusion in the rat model

L Langerman, MI Zakowski, B Piskoun…-… of pharmacological and…, 1995-Elsevier

… The plate was adjusted to maintain a constant temperature of 52.5 + 0.2 ”C (Hot
Plate Model D, IITC INC., Woodland Hills, CA). The animal was placed on the heated
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Neuroanatomical sites of action of neurotensin

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… Behavioral testing was begun one week after surgery. A hot plate (IITC, Inc., Model
35-D) was used to assess nociceptive threshold and was maintained at 55.0 -t 0.5 "C.
The latency for the animal to lick its hind or forepaw or jump off the…

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The behavioural effects of intrathecal galanin on tests of thermal and mechanical nociception in the rat

Z Wiesenfeld-Hallin, XJ XU, JX HAO…-Acta physiologica…, 1993-Wiley Online Library

… Only rats showing bilateral motor blockade were included in the study. The response of the rats
to noxious thermal stimuli was assessed with a hot plate (IITC, Woodland Hills, CA, USA)
maintained at 54k0.2 "C. The paw withdrawal response to noxious mechanical stimuli…

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Antinociceptive effects in mice after intrathecal injection of 5′-N-ethylcarboxamide adenosine

C Post-Neuroscience letters, 1984-Elsevier

… The tail-flick test was performed with an IITC Model 33 Analgesiameter, and an IITC Model
35-D Analgesiameter for the hot-plate test. In the tail-flick test, the intensity of the light beam was
adjusted to achieve a reaction latency of 3-4 s before the drug was administered…

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Intra-paragigantocellularis lateralis injection of orexin-A has an antinociceptive effect on hot plate and formalin tests in rat

E Erami, H Azhdari-Zarmehri , E Ghasemi-Dashkhasan…-Brain research, 2012-Elsevier

… Minor modifications. In these experiments, the hot-plate (Analgesia meter IITC, Life
Science, USA) apparatus was maintained at 52 ± 0.1 ° C. The animals, presenting
training latencies higher than 30 s, were excluded. Animals…

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Antagonism of nitrous oxide antinociception in the rat hot plate test by site-specific mu and epsilon opioid receptor blockade.

BL Hodges, MJ Gagnon, TR Gillespie …-… of Pharmacology and…, 1994-ASPET

… After a 5-mm exposure period, the animal was quickly removed from the box and dropped onto
a hot plate analgesiometer (IITC, Wood- land Hills, CA) with a Plexiglas enclosure (30 cm long
x 30 cm wide x 45 cm high) through which flowed the same concentration of N2O in 02…

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Hyperalgesia in mice lacking the Kv1. 1 potassium channel gene

JD Clark, BL Tempel-Neuroscience letters, 1998-Elsevier

… Hot plate assay was done as described by O'Callaghan and Holtzman [10] with equipment from
IITC… Taken together, the paw flick and hot plate data indicate that the effects of morphine are… of
focused light, Kv1.1 null mutants have shorter latencies, (2) using a hotplate assay in…

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Evaluation of the antinociceptive activity and acute oral toxicity of standardized ethanolic extract of the rhizome of Curcuma xanthorrhiza Roxb

S Devaraj, AS Esfahani, S Ismail , S Ramanathan…-Molecules, 2010-mdpi.com

… [11] with slight modifications. The hot plate test was assessed by the Incremental Hot plate (IITC
Life Sciences). The hot plate temperature was maintained at 55 ± 1 ºC. Prior to treatment, only
rats that showed response within 18 sec were selected for this study…

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Intrathecal γ-aminobutyric acidB (GABAB) receptor antagonist CGP 35348 induces hypersensitivity to mechanical stimuli in the rat

JX Hao, XJ Xu, Z Wiesenfeld-Hallin-Neuroscience letters, 1994-Elsevier

… And was averaged. The responses to noxious heat was tested by placing the rats
on a hot plate (IITC, Woodland Hills, CA, USA) maintained at 54 + 0.2 ° C and the
latency to licking a hindpaw was determined. All rats used in…

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