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Model Biological Research

High-throughput image acquisition system for zebrafish larvae

来源:本站 作者:玉研仪器 Time: 2016-09-28 Source: Site Author: Jade research instrument

Detailed introduction

VAST BioImager ™ Platform

Automatic operating system for high-throughput image acquisition of zebrafish larvae

 

系统是专门为需要采集大量 2-7 天斑马鱼幼体图像的研究者设计的。 The VAST BioImager system is specifically designed for researchers who need to acquire large numbers of zebrafish larvae for 2-7 days. Yanik 实验室开发的技术的基础上发展而来。 The system was developed on the basis of technology developed at the Massachusetts Institute of Technology's Yanik laboratory. 在采集图像之前自动完成斑马鱼幼体装载、定位、旋转等操作,避免了在进行高通量图像采集时对每条斑马鱼幼体人工操作的时间损耗和冗长的步骤。 VAST BioImager automatically completes zebrafish larvae loading, positioning, rotation and other operations before acquiring images, avoiding the time consuming and lengthy steps of manual operation on each zebrafish larvae during high-throughput image acquisition. At the same time, it is an assembled and expandable platform that can be installed on a variety of upright compound microscopes or stereo microscopes for high-resolution cell-level image acquisition.

 

主要特色: Main features of zebrafish larvae high-throughput image acquisition system :

 

·    斑马鱼研究的有力工具 Designed as a powerful tool for zebrafish research

自动处理图像采集前斑马鱼幼体的各种操作 Automatic processing of various operations of zebrafish larvae before image acquisition

避免人工操作的时间损耗和冗长的步骤 Avoid manual time consuming and lengthy steps

在软件上点击 “Load one Fish” VAST 就会装载好一个斑马鱼幼体 · Click "Load one Fish" on the software , VAST will load a zebrafish larva

系统可将斑马鱼幼体进行 360° 旋转进行定位操作者可根据自己的意愿选择方向,侧面、背面或者其他方向进行图像采集 The system can rotate the zebrafish larvae for 360 ° for positioning. The operator can choose the direction according to his wishes, and collect images on the side, back or other directions


High-resolution imaging

适用于高通量 & 高内涵筛选 Suitable for high-throughput & high-content screening

可安装在多种直立复式显微镜或者立体显微镜上 Can be mounted on a variety of upright compound microscopes or stereo microscopes

可安装在荧光显微镜上进行荧光图像采集 Can be mounted on a fluorescence microscope for fluorescence image acquisition

可选配的 LP 采样器,直接从多孔板中传送斑马鱼幼体到 VAST 进行图像采集 Optional LP sampler to transfer zebrafish larvae directly from multiwell plates to VAST for image acquisition

 

VAST BioImager的 相关文章: Related articles of zebrafish larvae high-throughput image acquisition system VAST BioImager :

High-throughput hyperdimensional vertebrate phenotyping.
Carlos Pardo-Martin, et.al., Nature Communications, Volume: 4, Article

number: 1467, DOI: doi: 10.1038 / ncomms2475
· Presenting VAST BioImager ™: A new modular, expandable platform to automate

the orientation of 2-7 day old zebrafish larvae for imaging.
Union Biometrica, Geel, Belgium, Union Biometrica, Holliston, MA, USA
Yanik lab, MIT, Boston, MA, USA
Fully automated cellular-resolution vertebrate screening platform with parallel

animal processing.
Chang TY, Pardo-Martin C, Allalou A, Wählby C, Yanik MF., Lab Chip. 2012 Feb
21; 12 (4): 711-6. Doi: 10.1039 / c1lc20849g.
High-throughput in vivo vertebrate screening.
Pardo-Martin C, Chang TY, Koo BK, Gilleland CL, Wasserman SC, Yanik MF., Nat

Methods. 2010 Aug; 7 (8): 634-6. Doi: 10.1038 / nmeth.1481.


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