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Location : ⎝⎛七乐彩⎞⎠ > Tissue Experiments in vitro> Microvascular tension measuring instrument in vitro
In vitro tissue experiment

Isolated microvascular tension measuring instrument

来源:本站 作者:玉研仪器 Time: 2016-10-15 Source: Site Author: Jade research instrument

Detailed introduction

Isolated microvascular tension measurement perfusion (perfusion) system is also called Radnoti Myograph System. This product is used to study the structure and function of isolated blood vessels. It can perform single or multiple small isolated blood vessels research The smallest blood vessel diameter can reach 60 microns.


It can be used in the fields of pharmacology, physiology, pathology, vasoactive mechanism and receptor research. The measured parameters are mainly: vascular wall thickness, comparative study of different blood vessels, assessment of local vascular reactivity, isotonic vascular tension measurement and Research on electrophysiological stimulation.


Has made successful applications in many areas:

(1) Research on the relaxing factor (NO), prostaglandin secreted by vascular endothelium, and hyperpolarizing factor secreted by vascular endothelium;

(2) Study on the mechanism of calcium and potassium channels in smooth muscle;

(3) Research on receptor localization and action characteristics;

(4) Research on hormones, neurotransmitters and action characteristics;

(5) Electrophysiological experiments, fluorescence measurement of intracellular ions and other substances;

(6) Study of drug effects, such as ACE-inhibitors, insulin and other related content;


At present, MYOGRAPH series products have been widely used in cardiovascular research and other fields. In the past two years, there have been more than 70 SCI papers published in research using this product. More than a dozen research institutes in China are using Radnoti Myograph System products for scientific research activities. Radnoti Myograph System's current customers include: Fudan University, Zhejiang University, Chinese University of Hong Kong, Third Military Medical University, Fourth Military Medical University, Hebei Medical University, Wenzhou Medical University, Shanghai Ruijin Hospital, Sichuan Chuanbei Medical College, etc. Angiotensometer is suitable for the study of one to four small blood vessels at the same time, with a blood vessel diameter between 60 microns and 3 mm. The two small steel wires passing through the inner cavity are fixed in a container of constant temperature oxygen and physiological saline solution to monitor the change of blood vessel tension. The whole process of blood vessel contraction and relaxation after adding different drugs is input to the computer through a tension sensor and controlled by a computer program. Completely record the tension changes of the vascular tube wall, and the vascular tension meter is particularly suitable for pharmacological research.


Available in multiple models and configurations


Radnoti Myograph System Single-channel Radnoti Myograph System 血管张力测量 系统 Microvascular perfusion and vascular tension measurement system


The system is suitable for vascular research between 60um and 3mm in diameter, and is used for laser confocal microscopy or other high imaging equipment. Two small steel wires passing through the lumen were fixed in a constant-temperature chamber of oxygen and physiological saline solution and monitored for changes in blood vessel tension. The whole process of blood vessel contraction and relaxation after adding different drugs is input to the computer through the tension sensor, and the tension change of the blood vessel wall is recorded under the control of the computer program. This system is particularly suitable for vascular pharmacology research.


Features and benefits:

● High-quality, high-precision research equipment;

Ideal equipment for large sample capacity detection;

● The sample can remain active for 12 hours;

Easy to use;

● Built-in heating and circuit control;


微血管灌流 血管张力测定系统 Four-channel microvascular perfusion vascular tension measurement system

This system is suitable for the study of two small blood vessels at the same time, and the blood vessel diameter is between 60um and 3mm. Two small steel wires passing through the lumen were fixed in a constant-temperature chamber of oxygen and physiological saline solution and monitored for changes in blood vessel tension. The whole process of blood vessel contraction and relaxation after adding different drugs is input to the computer through the tension sensor, and the tension change of the blood vessel wall is recorded under the control of the computer program. This system is particularly suitable for vascular pharmacology research.


Features and benefits:

● High-quality, high-precision research equipment;

● Two channels are engaged in experimental research at the same time;

Ideal equipment for large sample capacity detection;

● Pliers and needles,

Make the applied vessel ring diameter as small as 60 microns;

● The sample can remain active for 12 hours;

Easy to use;

  


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