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Dosing, sampling and poisoning

ALZET Osmotic Pumps

来源:本站 作者:玉研仪器 Time: 2016-12-19 Source: Site Author: Jade research instrument

Detailed introduction

Animal micro-administration osmotic capsule (pump ) Osmotic Pump

Alzet Osmotic Pumps are capsule-sized osmotic pumps that can be implanted subcutaneously or intraperitoneally in experimental animals, and can continuously and accurately deliver test agents at a rate of ul / hour directly or through a catheter for up to 6 weeks.


Alzet Osmotic Pumps meets the USP medical plastic material biocompatibility standard, suitable for implantation in experimental animals, for specific sites of administration, or introduction of medicament catheters into the site of action, such as: spinal cord and cranial cavity, intravascular, liver, spleen and Other organs and wounds.


Alzet brain infusion catheter to deliver test substance to CNS (Central Nervous System)

Alzet pumps has successfully delivered hundreds of drugs in 8,000 life science experiments around the world, including proteins, peptides, growth factors, Antisense in genetic research and treatment and new interference RNA (RNAi), antibiotics, chemotherapy Drugs, hormones, steroids and other short-acting compounds. Especially in the research of cardiovascular diseases and neurological diseases, animal models of various diseases can be established by continuous administration of ALZET Osmotic pumps, such as animal models of hypertension and Parkinson Parkinson's disease.

 

· More than 10,000 scientific papers published using ALZET ® Osmotic Pumps.

· More than 100 state-of-the-art national research institutes and universities and pharmaceutical factories have used the implantable capsule osmotic pump ALZET ® Osmotic Pumps to deliver drugs for pharmacological and toxicological experiments.

· In life science experimental research, implantable capsule osmotic pump Alzet pumps have become a good tool for drug delivery.


The medicament catheter can be introduced into different sites of action, such as: intracranial and spinal cord, intravascular, liver, spleen and other organs and wounds.

The main advantages of ALZET micro-osmotic pump

  • Ensure continuous exposure to test drugs at predetermined levels
  • Can perform protein and peptide administration during the cut-off period
  • Provides a simple method for chronic dosing in animals
  • Solve the inconvenience of night and weekend drug administration
  • Reduced manipulation and stress effects on laboratory animals
  • Small enough to be applied to mice, and young rats
  • Can be administered to almost any tissue
  • Cost-effective research tool



Alzet Osmotic Pumps meets the USP medical plastic material biocompatibility standards, suitable for implantation in experimental animals, specific drug delivery, or introduction of medicament catheters into the action site, such as: spinal cord and cranial cavity, intravascular, liver, Spleen and other organ tumors and wounds.

 

Alzet pumps have successfully delivered hundreds of drugs in 8,000 life science experiments around the world, including proteins, peptides, growth factors, Antisense in genetic research and treatment and new interference RNA (RNAi), antibiotics, chemotherapy Drugs, hormones, steroids and other short-acting compounds. Especially in the research of cardiovascular diseases and neurological diseases, continuous administration of ALZET Osmotic pumps can also establish animal models of various diseases, such as animal models of hypertension and Parkinson Parkinson's disease. Coupled with thousands of articles supporting it, it has played an irreplaceable role in many fields such as animal cell drug delivery, animal model construction, drug and molecular screening, and pharmacological and pharmacodynamic effects.



Micro-osmotic pump structure

Technical parameters of Alzet Osmotic Pumps:

There are 3 capacity sizes and 12 models of osmotic pressure pumps. The slow release rate and duration of each model of pump are different. See below:



Size, structure, material:




AlZET Infusion Set

The ALZET micro-osmotic pump provides direct brain drug infusion through a brain infusion accessory kit. Hundreds of thousands of literatures on neuroscience have been published. Infusion drugs include growth factors, siRNA, psychotropic drugs, and so on.

准确 的对特定部位进行输注 The addition of brain infusion kits and catheters allows ALZET to accurately infuse specific sites

PE polyethylene experimental catheter and Vinyl vinyl experimental catheter

The ALZET micro-osmotic pump can inject substances into the arteriovenous circulation, the brain, any organ cavity, or solid tissue through an experimental catheter.

Technical parameters of PE pipe and VINYL pipe:



ALZET catheter

Can be selected according to need: rat jugular vein catheter, rat femoral artery catheter, rat intrathecal catheter, mouse jugular vein catheter, mouse intrathecal catheter, etc.

PE drug delivery catheter

Intrathecal catheter



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