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Yuyan instruments take you to anesthetize experimental animals

来源:本站 作者:玉研仪器 Time: 2019-11-29 Source: Site Author: Jade research instrument

In various acute and chronic animal experiments, animals are usually deeply anesthetized to reduce or eliminate the animal's pain and keep it quiet, which is in line with animal welfare and can ensure that the experiment runs smoothly. Due to the different characteristics of narcotic drugs, animal drug tolerance varies between species or individuals, and the experimental content and requirements are different. Therefore, it is important to choose the type of narcotic drug, dosage and route of administration. The ideal anesthesia method should be easy to operate, while providing fast and adequate anesthesia maintenance, it has the characteristics of low side effects, reversibility, and small harm to animals and operators.
 

Animal anesthesia can be divided into injection anesthesia and inhalation anesthesia according to the types of drugs used. Injection anesthesia is currently widely used in China due to its simple operation and low cost. I believe that everyone has encountered the following embarrassing scenarios during the injection anesthesia experiment.




1) Overdose of anesthesia caused animal death
In most cases, people don't take it seriously when this happens, but when the dead animal is a precious species or an animal model that has been pulled hard for months, the sense of helplessness and frustration really makes people cry. . Think about it, it ’s hard to pull the big animal model, and finally it ’s the last critical moment, because the dose of anesthesia is not controlled, and it hangs up, who do we want to talk to?


2) The depth and duration of anesthesia are not sure, and the animal will wake up in advance
In the dimly-lit operating room, the operation is as usual. Suddenly, the pale-skinned animal in front of you widened your eyes and looked at you. His eyes are bright red, his limbs are twitching and struggling to come to you, the scene is comparable to Japanese and Korean horror movies, think of it to stimulate!
3) The duration of anesthesia is too long, and the animal cannot wake up for a long time. It needs a reversal agent, which delays the experimental process.
4) The sample size of the experiment is amazing.
5) .............
 
Animal injection anesthesia is difficult to precisely control the duration and depth of anesthesia. Most of its anesthetic drugs have some residuals in the body, and it has a significant inhibitory effect on the cardiovascular and respiratory system. It is highly toxic to liver and kidney. It is currently being replaced by inhalation anesthesia . Compared with injection anesthesia, inhalation anesthesia has the following characteristics:



The ABx series of small animal anesthesia machines provided by Shanghai Yuyan Scientific Instrument Co., Ltd. provides a variety of combined inhalation anesthesia solutions to help researchers play with inhalation anesthesia.  


  1. 型动物麻醉机 ABS animal anesthesia machine
Isoflurane is an isomer of enflurane. It is a colorless, clear liquid, volatile, and has a slight odor. It is the most commonly used inhalation anesthetic, and its induction and resuscitation are fast.
  • It is less biotransformed than enflurane and is almost completely cleared by the lungs. This means that it induces little to the liver drug enzyme system, and therefore has little interference with pharmacokinetic and toxicological tests.
  • There is no sympathetic nervous system excitement during anesthesia, which can slightly sensitize the heart to the effect of adrenaline and have a certain muscle relaxation effect. Isoflurane is more widely used in animal experiments.
Sevoflurane is a colorless, transparent liquid that is volatile, non-flammable, and non-irritating.
  • It is hardly involved in metabolism and biotransformation in the body, most of it is cleared by the lungs, and a small part is excreted by the kidneys, making it safer to use.
  • Compared with isoflurane, sevoflurane has a blood solubility of about half that of isoflurane, and MAC (minimum alveolar absorption concentration) is higher than isoflurane, so animals can induce, deepen anesthesia, and recover faster and more quickly. Conducive to long and deep surgery.
 
The host of the ABS isoflurane / sevoflurane anesthesia machine is imported from the original, with precise concentration control and long service life.



Yuyan ABS anesthesia machine has the following characteristics:
进口麻醉挥发主机 · Imported anesthesia volatile host
具有温湿度补偿功能,浓度控制精确 With temperature and humidity compensation function, precise concentration control
稳定的控制输出浓度,范围0-5% · Stable control output concentration, range 0-5%
通道数,标配单通道控制,可根据需求选配两通道、四通道、五通道 · Number of channels, standard single channel control, optional two channels, four channels, five channels according to requirements
适用动物:大鼠、小鼠、兔子、猴子等动物 · Applicable animals: rats, mice, rabbits, monkeys and other animals  


 
型动物麻醉机 2. ABF animal anesthesia machine
The ABF type adopts a domestic new-type anesthesia volatilizer host, with precise concentration control and similar functional characteristics to the ABS type anesthesia machine. Similarly, the ABF anesthesia machine is available in isoflurane and sevoflurane.



型动物麻醉机(异氟烷/七氟烷两种款式可选) 3. ABM animal anesthesia machine (isoflurane / sevoflurane two styles are optional)


ABM-type isoflurane anesthesia machine adopts the domestic old-fashioned anesthesia tank host with stable performance and affordable price. Compared with the ABS type anesthesia machine, it has no temperature and humidity compensation function, the concentration control accuracy is slightly worse, and the method of dosing is slightly more complicated.
The ABM type anesthesia machine is sufficient to meet the requirements of normal inhalation anesthesia, which is more cost-effective than imported equipment. ABM anesthesia machine is available in isoflurane and sevoflurane




型动物麻醉机(异氟烷/七氟烷两种款式可选) 4. ABK animal anesthesia machine (isoflurane / sevoflurane two styles are optional)


ABK type isoflurane anesthesia machine adopts the anesthesia tank mainframe imported from the UK, which has stable performance and overall performance similar to that of ABS type anesthesia machine with high cost performance.



型大动物麻醉机 5.ABL large animal anesthesia machine


ABL type anesthesia machine has the same functional characteristics as ABS type anesthesia machine, but it adds upgrade accessories such as filtration and reflux of sodium lime tank. It adopts floor stand structure and universal wheel design, which is more suitable for rabbits, dogs, monkeys, pigs, etc Big animal use




除此之外,我们还有MRI兼容的ABS核磁型麻醉机可供客户选择,欢迎来电咨询021-35183767 6. In addition, we also have MRI-compatible ABS nuclear magnetic anesthesia machine for customers to choose from, please call us at 021-335183767
 
 
Shanghai Yuyan Scientific Instrument Co., Ltd. has been committed to introducing advanced research equipment and technical means at home and abroad, and strives to provide professional and comprehensive scientific research solutions for domestic researchers!


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